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T2319 |
Acotiamide monohydrochloride trihydrate
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Acotiamide hydrochloride,YM-443 HCl,Z-338 HCl |
AChE
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Acotiamide monohydrochloride trihydrate (Z-338 HCl) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamid... |
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T31597 |
Ecabapide
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DQ2511,DQ 2511,DQ-2511 |
Others
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Ecabapide (DQ-2511) is a novel gastrointestinal motility promoter that significantly enhances gastric emptying in SHRSP.Ecabapide activates cyclic GMP-dependent housekeeping Cl- channels in rabbit gastric wall cells. |
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T17030 |
Tegoprazan
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ATPase
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Proton pump
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Tegoprazan is a potassium-competitive acid blocker and is a potent, oral active, and highly selective inhibitor of gastric H+/K+-ATPase. That could control gastric acid secretion and motility (IC50: ranging from 0.29-0.5... |
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T1052 |
Proglumide
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cholecystokinin
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Proglumide (Binoside) is a cholecystokinin antagonist, which blocks both the CCKA and CCKB subtypes. Proglumide is a drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is... |
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T70122 |
Acotiamide Methyl Ether
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Acotiamide Methyl Ether is a metabolite of Acotiamide -- an acetylcholinesterase inhibitor which has been shown to stimulate gastric motility and improve gastric motility dysfunction in rats. Acotiamide Hydrochloride has... |
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T68735 |
Ciclotropium (free base)
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Ciclotropium (free base) is quaternary ammonium compound with anticholinergic and parasympatholytic activity. Oral Cyclotropium bromide inhibited fasting and meal-stimulated colonic motility significantly without causing... |
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T78109 |
(Ala13)-Apelin-13 TFA
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'(Ala13)-Apelin-13 TFA acts as a potent antagonist of the apelin receptors (APJ) and impedes gastric motility via the vagal cholinergic pathway [1].' |
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T63237 |
Acotiamide hydrochloride
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Acotiamide hydrochloride is a selective, orally active, reversible acetylcholine ester (AChE) inhibitor (IC50: 1.79 μM) that increases gastric contractility, accelerates delayed gastric emptying, and can be used to study... |
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T22230 |
Acotiamide
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Acotiamide is an orally active, selective and reversible acetylcholinesterase ( AChE ) inhibitor, with IC 50 of 1.79 μM. Acotiamide is a gastroprokinetic agent that enhances gastric contractility and accelerates delayed ... |
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T25912 |
Oxypyrronium bromide
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L.D. 3055,Immetropan,LD 3055,LD3055,LD-3055 |
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Oxypyrronium bromide is an anticholinergic and spasmolytic agent containing quaternary ammonium. In animal models it inhibited gastric motility, hypotension induced by vagus stimulation or intravenation of acetylcholine;... |
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T75262 |
Relamorelin TFA
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Relamorelin (RM-131) TFA, a pentapeptide ghrelin analog, acts as a potent and selective agonist for the ghrelin/growth hormone secretagogue receptor (GHSR), with a K_i of 0.42 nM for the GHS-1a receptor. This compound is... |
